| Clarithromycin tablets
Primary metabolism of tolterodine is carried out with the participation of CYP2D6. However, part of the population lacking CYP2D6, metabolism occurs with the participation of CYP3A. In this population filing
Pregnancy and lactation
Application in I trimester of pregnancy is contraindicated.
Application in II and III trimester of pregnancy is possible only when the intended benefits to the mother outweighs the potential risk to the fetus.
Clarithromycin tablets
If necessary, use during lactation should stop breastfeeding.
Side effects
From the digestive system: often - diarrhea, vomiting, dyspepsia, nausea, pain in the abdomen; rarely - esophagitis, gastroesophageal reflux disease, gastritis, rectalgia, stomatitis, glossitis, abdominal distension, constipation, dry mouth, belching, flatulence, increased bilirubin concentration in the blood, increased ALT, ACT, GGT, alkaline phosphatase, LDH, cholestasis, hepatitis , including cholestatic and hepatocellular; the frequency is unknown - acute pancreatitis, a change in the language of color and teeth, hepatic failure, cholestatic jaundice.
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