| Clarithromycin 250mg aution should be used clarithromycin in patients with renal insufficiency, moderate and severe; hepatic failure secondary to severe, with coronary artery disease, severe cardiac insufficiency, hypomagnesemia, marked bradycardia (less than 50 beats / min.); simultaneously with benzodiazepines, such as alprazolam, triazolam, midazolam for the on / in; concurrently with other
Clarithromycin 250mg
ototoxic drugs, particularly aminoglycosides; simultaneously with drugs that are metabolised isoenzymes CYP3A (including carbamazepine, cilostazol, cyclosporine, disopyramide, methylprednisolone, omeprazole, indirect anticoagulants, quinidine, rifabutin, sildenafil, tacrolimus, vinblastine, simultaneously with inductors CYP3A4 (including rifampicin , phenytoin, carbamazepine, phenobarbital, St. John's wort) simultaneously with statins, which are not dependent on metabolism isoenzyme CYP3A (including fluvastatin), simultaneously with the slow calcium channels blockers which are metabolized isozymes CYP3A4 (including verapamil, amlodipine, diltiazem) simultaneously with class IA antiarrhythmic agents (quinidine, procainamide) and class III (dofetilide, amiodarone, sotalol).
Clarithromycin 250mg
Between the antibiotics from the macrolide group observed cross-resistance.
Treatment with antibiotics alters the normal flora of the intestine, so it is possible the development of superinfection caused by resistant microorganisms.
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